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王洋 教授

发文时间:2017-05-05 22:10

 

王洋 教授 博士生导师

研究方向:生物活性物质利用

联系方式:ywang1971@hotmail.com

个人经历

1989-1993  东北师范大学化学专业理学学士

1993-1996  黑龙江大学有机化学专业理学硕士

1997-2000   东北林业大学植物学专业理学博士

1996.07 -2010.07  东北林业大学 讲师、副教授、教授、博士生导师

2002.01-2003.08  美国德克萨斯州立大学医学院分部、斯特林癌症研究基金会博士后

2006.04-2008.08  美国休斯顿大学药学院、斯特林癌症研究基金会研究科学家(Research Scientist)

2010.07-东北林业大学盐碱地环境资源研究中心教授、博士生导师

发表论文

1.Wang Y, Chen Y, Zhang M , Qu H, Zheng J, Pang Q, Yan X*. Safety evaluation of liposomal nanohybrid cerasomes and their application in the release of 10-hydroxycamptothecin. RSC Advances, 2016, 6: 16292-16300.

2.Jian Zheng, Ting Chan, Ling Zhu, Xiufeng Yan, Zhisong Cao, Yang Wang* & Fanfan Zhou*. The inhibitory effects of camptothecin (CPT) and its derivatives on the substrate uptakes mediated by human solute carrier transporters (SLCs). Xenobiotica, 2016, 46(9): 831-840

3.Zhiwei Hu, Ziming Wang, Yong Liu, Yan Wu, Xuejiao Han, Jian Zheng, Xiufeng Yan, and Yang Wang*. 2015. Metabolite Profile of Salidroside in Rats by Ultraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry and High-Performance Liquid Chromatography Coupled with Quadrupole-Linear Ion Trap Mass Spectrometry. Journal of Agricultural and Food Chemistry, 63, 8999−9005

4.Changmin Shao, Jian Zheng, Bo Fan, Shaman Luo, Jixiang Lin, Tao Yu, Xiufeng Yan, Yang Wang*. 2015. Tissue distribution of 10-methoxycamptothecin and its metabolite 10-hydroxycamptothecin in rats by a RP-HPLC method with fluorescence detection/UV detection. Analytical Methods, 7, 7690–7696

5.Weimin Ding, Miao Sun, Shaman Luo, Tao Xu, Yibo Cao, Xiufeng Yan, Yang Wang*. A 3D QSAR Study of Betulinic Acid Derivatives as Anti-Tumor Agents Using TopomerCoMFA: Model Building Studies and Experimental Verification, Molecules, 18(9), 10228-10241, 2013

6.Zhiwei Hu, Na Guo, Ziming Wang, Yong Liu, Yu Wang, Weimin Ding, Dehui Zhang, Yang Wang, Xiufeng Yan*. 2013Development and validation of an LC-ESI/MS/MS method with precolumnderivatization for the determination of betulin in rat plasma. Journal of Chromatography B, 939, 38-44,

7.Jian Zheng, Honghong Guo, Na Guo, Wei Ma, Lijia Jing, Rui Zhang, Zhifei Dai, Xiufeng Yan, Yang Wang*, Zhenyue Wang*. 2012. A two-step pH-dependent liquid-liquid extraction combined with HPLC-fluorescence method for the determination of 10-hydroxycamptothecin in mouse liver tissue. Pharmaceutical Biology, 50 (8): 954-961

8.Jian Zheng, Rui Zhang, Changmin Shao, Zhiwei Hu, Di Wang, Tao Yu, Xiufeng Yan, Yang Wang*. 2012. Development and validation of a RP-HPLC method with fluorescence detection for simultaneous determination of 10-methoxycamptothecin and its metabolite 10-hydroxycamptothecin in rat plasma. Journal of Chromatography B, 903: 81– 87

9.Na Guo, Zhiwei Hu, Xiaoxu Fan, Jian Zheng, Dehui Zhang, Tao Xu, Yang Wang*, Haiying Li. 2012. Simultaneous determination of salidroside and its aglycone metabolite p-tyrosol in rat plasma by liquid chromatography-tandem mass spectrometry. Molecules, 17(4): 4733-4754.