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井立佳 副教授

发文时间:2017-05-05 22:39

 

井立佳 副教授 硕士生导师

研究方向

1. 纳米药物递送系统及生物影像探针的研制

2. 微纳米医学材料的筛选开发

3. 纳米尺度下的生物效应研究

联系方式:jinglijia@nefu.edu.cn

 

学习及工作经历

2004/09-2008/07   学士 专业:生物科学 齐齐哈尔大学

2008/09-2011/07   硕士 专业:细胞生物学 东北林业大学

2011/09-2016/01   博士 专业:生物医学工程 哈尔滨工业大学

2016/05至今      副教授/硕导 盐碱地生物资源环境研究中心

 

研究经历

2008/9-2011/7     东北林业大学 喜树碱衍生物的合成与抗肿瘤活性筛选

2011/9-2012/12 哈尔滨工业大学 多功能纳米药物载体的研制

2012/12-2014/12 北京大学     基于纳米技术的光热治疗研究

2014/12-2015/12 中科院自动化所 影像介导的肿瘤治疗技术开发

2016/5  至今     东北林业大学 基于天然活性物质的纳米抗肿瘤制剂的研究

 代表性论文

1.Jing Lijia, Shao Shangmin, Wang Yang, Yang Yongbo, Yue Xiuli, Dai Zhifei. Hyaluronic Acid Modified Hollow Prussian Blue Nanoparticles Loading 10-hydroxycamptothecin for Targeting Thermochemotherapy of Cancer, Theranostics, 2016, 6(1): 40-53. SCI收录(IF: 8.854, JCR-Q1区)

2.Lijia Jing, Di Fan, Jiyun Shi, Yaqian Li, Renfa Liu, Jie Tian, Fan Wang, Zhifei Dai*. 177Lu-labeled cerasomes encapsulating indocyanine green for cancer therapy. ACS Applied Materials & Interfaces, 2015, 7, 22095-22105. SCI收录(IF: 7.145, JCR-Q1区)

3.Lijia Jing, Xiaolong Liang, Xiaoda Li, Li Lin, Yongbo Yang, Xiuli Yue, Zhifei Dai*. Mn-porphyrin conjugated Au nanoshells encapsulating doxorubicin for potential magnetic resonance imaging and light triggered synergistic therapy of cancer. Theranostics, 2014, 4: 858-871. SCI收录(IF: 8.854, JCR-Q1区)

4.Lijia Jing, Xiaolong Liang, Zijian Deng, Shanshan Feng, Xiaoda Li, Maomao Huang, Changhui Li, Zhifei Dai*. Prussian blue coated gold nanoparticles for simultaneous photoacoustic/CT bimodal imaging and photothermal ablation of cancer. Biomaterials, 2014, 35: 5814-5821. SCI收录(IF: 8.387, JCR-Q1区)

5.Lijia Jing, Xiaolong Liang, Xiaoda Li, Yongbo Yang, Xiuli Yue*, Zhifei Dai*. Covalent attachment of Mn-porphyrin onto doxorubicin-loaded PLA nanoparticles for potential MRI and pH-sensitive drug delivery, Acta Biomaterialia, 2013, 9: 9434–9441. SCI收录(IF: 6.008, JCR-Q1区)

6.Xiaolong Liang, Zijian Deng, Lijia Jing (共同第一作者), Xiaoda Li, Changhui Li*, Maomao Huang, Zhifei Dai*. Prussian blue nanoparticles operate as a contrast agent for enhanced photoacoustic imaging. Chemical Communications, 2013, 49: 11029-11031. SCI收录(IF: 6.567, JCR-Q1区)

7.Yongbo Yang, Lijia Jing, Xiaoda Li, Li Lin, Xiuli Yue, Zhifei Dai *, Hyaluronic Acid Conjugated Magnetic Prussian Blue@Quantum Dot Nanoparticles for Cancer Theranostics, Theranostics, 2017. 7(2),SCI收录(IF: 8.854, JCR-Q1区)

8.Renfa Liu, Lijia Jing, Dong Peng, Yong Li, Jie Tian, Zhifei Dai. Manganese (II) chelate functionalized copper sulfide nanoparticles for efficient magnetic resonance /photoacoustic dual-modal imaging guided photothermal therapy, Theranostics, 2015, 5(10): 1144-1153. SCI收录(IF: 8.854, JCR-Q1区)

9.Liang Xiaolong, Li Yanyan, Li Xiaoda, Jing Lijia, Deng Zijian, Yue Xiuli, Li Changhui, Dai Zhifei. PEGylated Polypyrrole Nanoparticles Conjugating Gadolinium Chelates for Dual-Modal MRI/Photoacoustic Imaging Guided Photothermal Therapy of Cancer, Advanced Functional Materials, 2015, 25(9):1451-1462. SCI收录(IF: 11.382, JCR-Q1区)

10.Xiaolong Liang, Jing Gao, Lingdong Jiang, Jianwen Luo, Lijia Jing, Xiaoda Li, Yushen Jin, Zhifei Dai. Nanohybrid liposomal cerasomes with good physiological stability and rapid temperature responsiveness for HIFU triggered local chemotherapy of cancer, ACS Nano, 2015, 9(2):1280-1293. SCI收录(IF: 13.334, JCR-Q1区)

11.Xiaolong Liang, Xiaoda Li, Lijia Jing, Xiuli Yue and Zhifei Dai*. Theranostic porphyrin dyad nanoparticles for magnetic resonance imaging guided photodynamic therapy, Biomaterials, 2014, 35(24): 6379-6388. SCI收录 (IF: 8.387, JCR-Q1区)

 

授权专利

10-甲氧基喜树碱衍生物、制备方法和用途,ZL201110169891.0.。

Derivate, preparation method and use of 10-methoxycamptothecin, US 9034894 B2。

科研项目

东北林业大学高层次引进人才启动项目

黑龙江省博士后特别资助

国家博士后基金